2-cyanoethyl (((2S,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-(2-methoxyethoxy)-3-(((4-methoxyphenyl)diphenylmethyl)amino)tetrahydrofuran-2-yl)methyl) diisopropylphosphoramidite CAS NO.2299277-80-6

HitGen Inc It has been reported that alterations in base or sugar moieties can lead to significant changes in pharmacokinetic and pharmacodynamic properties of nucleosides. Modification of base and sugar ring of known actives is one of the main strategies in nucleoside drug research. The generation of unnatural active isomer also expands the approach diversity of developing nucleoside drugs. HitGen has developed a few of non-conventional approaches involving stereo- and enantio-selective reactions for the modification of naturally occurring nucleosides to make this type of compounds more accessible within reasonable time and competitive price.The professional and experienced R&D team at HitGen could meet various demand in a timely, fast and efficient manner, and achieve nearly 100% successful rate and >95% on-time delivery rate, HitGen has won the recognition and trust of many customers. Well-equipped facilities, professional project management and strict quality control system could maximally guarantee successful collaboration. Guided by innovation and centered on customer, HitGen is dedicated to providing comprehensive and customized solutions for nucleosides drug discovery in an efficient and cost-effective way.

Useful intermediate or API